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Nodular prurigo | DermNet NZ

What is the cause of nodular prurigo?. The cause of nodular prurigo is unknown. It is uncertain whether scratching leads to the nodules or if the nodules appear before they are scratched. The reason for the nodules, the inflammation and the increased activity and size of nerves in the skin is under investigation but remains unknown.. Nodular prurigo may commence as an insect bite reaction or ...